Papan C, Reifenrath K, Last K, Attarbaschi Andishe A, Graf N, Groll AH, Hübner J, Laws HJ, Lehrnbecher T, Liese JG, Martin L, Tenenbaum T, Vieth S, von Both U, Wagenpfeil G, Weichert S, Hufnagel M, Simon A (2023).
Antimicrobial use in pediatric oncology and hematology: a cross-sectional, multi-center point-prevalence study with a multi-step qualitative adjudication process.
Lancet Regional Health - Europe; DOI: 10.1016/j.lanepe.2023.100599
Abstract
Brunner HI, Foeldvari I, Alexeeva E, Ayaz NA, Calvo Penades I, Kasapcopur O, Chasnyk VG, Hufnagel M, Zuber Z, Schulert GS, Ozen S, Rakhimyanova A, Ramanan A, Scott C, Sozeri B, Zholobova E, Martin R, Zhu X, Whelan S, Pricop L, Martini A, Lovell DJ and Ruperto N, on behalf of Paediatric Rheumatology INternational Trials Organization (PRINTO) and Pediatric Rheumatology Collaborative Study Group (PRCSG) (2023).
Secukinumab in enthesitis-related arthritis and juvenile psoriatic arthritis: a randomised, double-blind, placebo-controlled, treatment withdrawal, phase 3 trial.
Annals of Rheumatic Diseases 82:154-60. DOI: 10.1136/ard-2022-222849
Abstract
Lohrmann F, Hufnagel M, Kunze M, Afshar B, Creti R, Detcheva A, Kozakova J, Rodriguez-Granger J, Skov Sørensen UB, Margarit I, Maione D, Rinaudo D, Orefici G, Telford J, de la Rosa Fraile M, Kilian M, Efstratiou A, Berner R, Melin P, for the DEVANI study group (2022).
Neonatal invasive disease caused by Streptococcus agalactiae in Europe: the DEVANI multi-center study.
Infection (Online ahead of print). DOI: 10.1007/s15010-022-01965-x
Abstract
Broehaert IJ, Klein A, Windschall D, Rogalski B, Weller-Heinemann F, Oommen P, Küster M, Foeldvari I, Minden K, Hospach A, Hufnagel M, Berger T, Geikowski T, Quietzsch J, Horneff G (2022).
Development of inflammatory bowel disease in children with juvenile idiopathic arthritis treated with biologics.
Journal of Pediatric Gastroenterology and Nutrition, (online ahead of print). DOI: 10.1097/MPG.0000000000003656
Abstract
Papan C, Reifenrath K, Last K, Attarbaschi A, Graf N, Groll AH, Hübner J, Laws HJ, Lehrnbecher T, Liese J, Martin L, Tenenbaum T, Weichert S, Vieth S, von Both U, Hufnagel M, Simon A, for the Study Group “Antibiotic Stewardship” of the DGPI and the Study Group “Febrile Neutropenia” of the GPOH (2022).
Study protocol for a multi-center point-prevalence study with qualitative expert panel assessment of antimicrobial use in pediatric oncology and hematology.
JMIR Research Protocols 11:e35774
Abstract
Sorg AL, Bergfeld L, Jank M, Corman V, Semmler I, Görtz A, Beyerlein A, Verjans E, Wagner N, von Bernuth H, Lander F, Weil K, Hufnagel M, Spiekerkoetter U, Cho-Ming C, Nährlich L, Muntau AC, Schulze-Sturm U, Hansen G, Wetzke M, Jung AM, Niehues T, Fricke-Otto S, von Both U, Huebner J, Behrends U, Liese JG, Schwerk C, Drosten C, von Kries R, Schroten H (2022).
Cross-sectional seroprevalence surveys of SARS-CoV-2 antibodies in children in Germany, June 2020 to May 2021.
Nature Communications, 13, 3128 (2022). DOI: 0.1038/s41467-022-30482-6
Abstract
Reiser C, Klotsche J, Hospach T, Berendes R, Schnabel A, Jansson A, Hufnagel M, Groesch N, Niewerth M, Minden K, Girschick H (2021).
First year follow-up of children with chronic non-bacterial osteomyelitis – and analysis of the German National Pediatric Rheumatologic Database 2009-2018.
Arthritis Research & Therapy, 23:281.
Abstract
Jakob A, Hufnagel M (2021).
Follow-up on Children with PIMS. [Nachsorge von Kindern mit PIMS].
Deutsches Ärzteblatt, 118:A1814-1816. German.
Abstract
Geweniger A, Janda A, Eder K, Fressle R, Kannan CV, Fahnenstich H, Elze M, Müller C, Henneke P, Hufnagel M, Elling R (2021).
High diagnostic yield of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the diagnosis of pediatric pulmonary tuberculosis.
BMC Infectious Diseases, 21:946.
Abstract
Cook A, Sharland M, Yau Y, PediBSI Group, Bielicki J (2021).
Improving empiric antibiotic prescribing in pediatric bloodstream infections: a potential application of weighted-incidence syndromic combination antibiograms (WISCA).
Expert Reviews of Anti-Infective Therapy. DOI: 10.1080/14787210.2021.1967145 (published online 15 Sept. 2021) .
Abstract
Bemtgen X, Klingel K, Hufnagel M, Janda A, Bode C, Staudacher DL, Supady A, Jandova I (2021).
Case report: Lymphohistiocytic myocarditis with severe cardiogenic shock requiring mechanical cardiocirculatory support in Multisystem Inflammatory Syndrome following SARS-CoV-2 infection.
Frontiers in Cardiovascular Medicine, 8:716198.
Abstract
Holstiege J, Bätzing J, Akmatov MK, Tillmann R, Hufnagel M, Hübner J, Berner R, Simon A (2021).
Reduction of outpatient antibiotic prescriptions for children and adolescents in Germany 2010-2019. Regional development in the German statuatory health insurance regions. [Rückgang der ambulanten Antibiotikaverordnungen bei Kindern und Jugendlichen in Deutschland 2010-2019. Regionale Entwicklung in den deutschen KV-Regionen.]
Monatsschrift Kinderheilkunde (published online 30 July 2021). German.
Abstract
Kohns Vasconcelos M, Loens K, Sigfrid L, Iosifidis E, Epalza C, Dona D, Papachristou S, Roilides E, Gijon M, Rojo P, Minotti C, Da Dalt L, Islam S, Jarvis J, Syggelou A, Tsolia M, Nyirenda Nyang’wa M, Keers S, Renk H, Gemmel AL, D’Amore C, Ciofi degli Atti M, Rodriguez-Tenreiro Sanchez C, Martinon-Torres F, Burokiene S, Goetghebuer T, Spoulou V, Riordan A, Calvo C, Gkentzi D, Hufnagel M, Openshaw P, Goossens H, Leven G, Fraaij P, Giaquinto C, Bielicki JA, Horby P, Sharland M (2021).
Aetiology of acute respiratory tract infection in pre-school children requiring hospitalisation in Europe – results from the PED-MERMAIDS multi-centre case-control study.
BMJ Open Respiratory Research, 8:e000887.
Abstract
Lohrmann F, Berg A, Wicker E, Imm A, Krause G, Zürn K, Berner R, Hufnagel M, Lander F (2021).
Prevalence of Capsular Serotype, Pilus Island Distribution, and Antibiotic Resistance in Pediatric and Adult Invasive Group B Streptococcus Isolates: Data From a Nationwide Prospective Surveillance Study in Germany.
Pediatric Infectious Diseases, 40:76-82, (published online 16 Nov 2020).
Abstract
Kohns Vasconcelos M, Renk H, Popielska J, Nyirenda Nyang’wa M, Burokiene S, Gkentzi D, Gowin E, Donà D, Villanueva-Medina S, Riordan A, Hufnagel M, Eisen S, Da Dalt L, Giaquinto C, Bielicki JA (2021).
SARS-CoV-2 testing and infection control strategies in European paediatric emergency departments during the first wave of the pandemic.
European Journal of Pediatrics, 180:1299-1305.
Abstract
Ruperto N, Brunner H, Ramanan A, Horneff G, Cuttica R, Henrickson M, Lopez JA, Boteanu AL, Calvo Penades I, Minden K, Schmeling H, Hufnagel M, Weiss JE, Pardeo M, Nanda A, Roth J, Rubio-Perez N, Hsu JC, Wimalasundera S, Wells C, Bharucha K, Douglass W, Bao M, Mallalieu NL, Martini A, Lovell D, De Benedetti F for the Paediatric Rheumatology International Trial Organization (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG) (2021).
Subcutaneous dosing regimen of tocilizumab in children with systemic or polyarticular juvenile idiopathic arthritis.
Rheumatology, 60:4568-4580.
Abstract
Quartier P, Alexeeva E, Tamàs C, Chasnyk V, Wulffraat N, Palmblad K, Wouters C, Brunner H, Marzan K, Schneider R, Horneff G, Martini A, Anton J, Wei X, Slade A, Ruperto N, Abrams K; Pediatric Rheumatology International Trials Organization (PRINTO), the Pediatric Rheumatology Collaborative Study Group (PRCSG) (2021).
(* Dr. Markus Hufnagel is a contributing member of the PRINTO Study Group.)
Tapering Canakinumab Monotherapy in Patients with Systemic Juvenile Idiopathic Arthritis in Clinical Remission: Results from an Open-label, Randomized Phase IIIb/IV Study.
Arthritis Rheumatology 73:336-346.
Abstract
Jakob A, Schachinger E, Klau S, Hufnagel M, van der Werf Grohmann N, Stiller B, Lehner A, Ulrich S (2020).
Evaluation of serum osteopontin levels as biomarkers for children with Kawasaki disease.
Annals of Cardiology and Vascular Medicine, 3:1035.
Abstract
Walser M, Hermann M, Hufnagel M, Haas NA, Fischer M, Dalla-Pozza R, Jakob A (2020).
Anakinra and etanercept combination treatment in a child with severe, non-responsive Kawasaki disease.
Pediatric Infectious Diseases Journal 39:e310-e313.
Abstract
Armann J, Diffloth N, Simon A, Doenhardt M, Hufnagel M, Trotter A, Schneider DT, Hübner J, Berner J (2020).
Hospital admission in children and adolescents with COVID-19—early results from a national survey conducted by the German Society for Pediatric Infectious Diseases (DGPI). [Hospitalisierungen von Kindern und Jugendlichen mit COVID-19 – erste Ergebnisse eines deutschlandweiten Surveys der deutschen Gesellschaft für Pädiatrische Infektiologie (DGPI)].
Deutsches Ärzteblatt 117:373-374. German.
Abstract
Zürn K, Lander F, Hufnagel M, Monecke S, Berner R (2020).
Microarray analysis of Group B streptococci causing invasive neonatal early- and late-onset infection.
Pediatric Infectious Diseases Journal 39:449-453.
Abstract
Janda A, Eder K, Fressle R, Geweniger A, Diffloth N, Heeg M, Binder N, Sitaru A, Rohr J, Henneke P, Hufnagel M, Elling R. (2020).
Comprehensive infectious disease screening in a cohort of unaccompanied refugee minors in Germany from 2016 to 2017: A cross-sectional study.
PLoS Medicine, 17(3): e1003076.
Abstract
Kuntz M, Kohlfürst DS, Feiterna-Sperling C, Krüger R, Baumann U, Buchtala L, Elling R, Grote V, Hübner J, Hufnagel M, Kaiser-Labusch P, Liese J, Otto EM, Rose MA, Schneider C, Schuster V, Seidl M, Sommerburg O, Vogel M, von Bernuth H, Weiß M, Zimmermann T, Nieters A, Zenz W, and Henneke P for the NTMkids consortium (2020).
Season, sex and surgery: Risk factors for complicated lymphadenitis caused by non-tuberculous mycobacteria in children.
Emerging Infectious Diseases 26:579-586.
Abstract
Klein A, Klotsche J, Hügle B, Minden K, Hospach A, Weller-Heinemann F, Schwarz T, Dressler F, Trauzeddel R, Hufnagel M, Foeldvari I, Borte M, Kuemmerle-Deschner J, Brunner J, Oommen PT, Föll D, Tenbrock K, Urban A, Horneff G (2020).
Long-term surveillance of biologic therapies in systemic-onset juvenile idiopathic arthritis. Data from the German BIKER registry.
Rheumatology 59:2287-2298.
Abstract
Konrad P, Hufnagel M, Berner R, Töpfner N (2020).
Long-term, single-center surveillance of non-invasive group A streptococcal (GAS) infections, emm types and emm clusters.
European Journal of Clinical Microbiology and Infectious Diseases 39:273-280.
Abstract
Bélard S, Brand J, Schulze-Sturm U, Janda A, von Both U, Tacoli C, Alberer M, Kempf C, Stegemann MS, Krüger R, Varnholt V, Blohm M, Reiter K, Zoller T, Suttorp N, Mall M, von Bernuth H, Gratopp A, Hübner J, Hufnagel M, Kobbe R, Kurth F (2019).
Intravenous Artesunate for Imported Severe Malaria in Children Treated in Four Tertiary Care Centers in Germany: A Retrospective Study.
Pediatric Infectious Diseases Journal 38:e295-e300.
Abstract
Elling R, Böttcher S, du Bois F, Müller A, Prifert C, Weissbrich B, Hofmann J, Korn K, Eis-Hübinger A-M, Hufnagel M, Panning M (2019).
Epidemiology of Human Parechovirus Type 3 Upsurge in 2 Hospitals, Freiburg, Germany, 2018.
Emerging Infectious Diseases 25:1384-1388.
Abstract
Hsia Y, Lee BR, Versporten A, Yang Y, Bielicki J, Jackson C, Newland J, Goossens H, Magrini N, Sharland M on behalf of the GARPEC and Global-PPS networks (2019).
*Dr. Hufnagel is a contributing member of the GARPEC and Global-PPS networks.
Using the WHO Access/Watch/Reserve classification to define patterns of hospital antibiotic use: analysis of pediatric point prevalence survey data from 56 countries. The first AWaRe PPS.
Lancet Global Health 7:e861-871.
Abstract
Brunner HI, Holland MJ, Beresford MW, Ardoin SP, Appenzeller S, Silva CA, Flores F, Goilav B, Avar Aydin PO, Wenderfer SE, Levy DM, Ravelli A, Khubchandani R, Avcin T, Klein-Gitelman MS, Ruperto N, Feldman BM, Ying J; Paediatric Rheumatology International Trial Organisation and Pediatric Rheumatology Collaborative Study Group (2019)
*Dr. Hufnagel is a contributing member of the Paediatric Rheumatology International Trial Organization.
American College of Rheumatology Provisional Criteria for Clinically Relevant Improvement in Children and Adolescents With Childhood-Onset Systemic Lupus Erythematosus.
Arthritis Care Res 71:579-90.
Abstract
Meyer K, Volkmann A, Hufnagel M, Schachinger E, Klau S, Horstmann J, Berner R, Fischer M, Lehner A, Haas N, Ulrich S, Jakob A (2019)
Breastfeeding and vitamin D supplementation reduce the risk of Kawasaki disease in a German population-based case-control study.
BMC Pediatrics. 2019 Feb 26;19(1):66.
Abstract
Wicker E, Lander F, Weidemann F, Hufnagel M, Berner R, Krause G (2019)
Group B Streptococci: Declining Incidence in Infants in Germany.
Pediatric Infectious Diseases Journal. 38:516-519.
Abstract
Lehrnbecher T, Groll AH, Agyeman P, Amman RA, Attarbaschi A, Behrends U, Berger C, Hamprecht A, Hufnagel M, Laws HJ, Scheler M, Temme C, Vieth S, Simon A für die Arbeitsgemeinschaften “Infektionen” der GPOH und “Fieber bei Neutropenie” der DGPI (2018)
Recommendations for Diagnostics and Therapy of Children with Cancer Presenting with Fever and Neutropenia - Comparison of Two Current Guidelines. [Empfehlungen zur Diagnostik und Therapie bei krebskranken Kindern mit Fieber und Granulozytopenie - Vergleich zweier aktueller Leitlinien].
Klinische Pädiatrie. 230:115-121. German.
Abstract
Hufnagel M, Versporten A, Bielicki J, Drapier N, Sharland M, Goossens H, for the ARPEC Project Group (2018)
High rates of prescribing for prophylaxis in children and neonates: Results from the Antibiotic Resistance and Prescribing in European Children Point Prevalance Survey (ARPEC-PPS).
Journal of the Pediatriatric Infectious Disease Society. 8:143-151.
Abstract
Pschibul A, Janzarik WG, Franck P, Hufnagel M, Beck C, Korinthenberg R (2018)
Cystic encephalomalacia following vasculopathy and vasospasm of proximal intracranial arteries due to pneumococcal meningitis in a young infant.
Neuropediatrics. 49:213-216.
Abstract
Jakob A, von Kries R, Horstmann J, Hufnagel M, Stiller B, Berner R, Schachinger E, Meyer K, Obermeier V (2018)
Failure to predict high risk Kawasaki disease patients in a population-based study cohort in Germany.
Pediatric Infectious Disease Journal. 37:850-855.
Abstract
Schwarz T, Oommen PT, Windschall D, Weissbarth-Riedel E, Trauzeddel R, Grote V, von Bismarck P, Morbach H, Hofmann C, Holl-Wieden A, Hügle B, Schnabel A, Dedeoglu F, Ferguson PJ, Zhao Y, Borte M, Haas JP, Hufnagel M, Hedrich CM, Girschick HJ, Jansson AF für die PRO-KIND CNO-Projektgruppe (2018)
Protocols for classification, monitoring and therapy in pediatric rheumatology (PRO-KIND): Chronic non-bacterial osteomyelitis (CNO). [HarmProtokolle zur Klassifikation, Überwachung und Therapie in der Kinderrheumatologie (PRO-KIND): Chronisch nicht-bakterielle Osteomyelitis (CNO)].
Arthritis + Rheuma 38:282-288. German.
Abstract
Hinze CH, Holzinger D, Lainka E, Haas JP, Speth F, Kallinich T, Rieber N, Hufnagel M, Jansson A, Hedrich C, Winowski H, Berger T, Foeldvari I, Ganser G, Hospach T, Huppertz H-I, Mönkemöller K, Neudorf U, Weißbarth-Riedel E, Wittkowski H, Horneff G, Foell D; PRO-KIND SJIA project (2018)
Practice and consensus-based diagnostic strategies in diagnosing and managing systemic juvenile idiopathic arthritis in Germany.
Pediatric Rheumatology Online Journal 16:7.
Abstract
Ingegnoli F, Ughi N, Dinsdale G, Orenti A, Boracchi P, Allanore Y, Foeldvari I, Sulli A, Cutolo M, Smith V, Herrick AL, EULAR Study Group on Microcirculation in Rheumatic Diseases (2017)
An international SUrvey on non‑iNvaSive tecHniques to assess the mIcrocirculation in patients with RayNaud’s phEnomenon (SUNSHINE survey).
Rheumatology International 37:1879-1890.
Abstract
Hinze CH, Holzinger D, Lainka E, Haas JP, Speth F, Kallinich T, Minden K, Rieber N, Hufnagel M, Jansson A, Hedrich C, Winowski H, Horneff G, Foell D für die PRO-KIND SJIA-Projektgruppe (2017)
Harmonization of diagnostics and therapy of systemic-onset juvenile idiopathic arthritis in Germany: Process description and key messages. [Harmonisierung der Diagnostik und Therapie der systemischen juvenilen idiopathischen Arthritis in Deutschland: Prozessbeschreibung und Kernaussagen].
Arthritis + Rheuma 37:250-259. German.
Citation
Poppert S, Heideking M, Agostini HJ, Fritzenwanker M, Wüppenhorst N, Muntau B, Henneke P, Kern WV, Krücken J, Junker B, Hufnagel M (2017)
Diffuse unilateral subacute neuroretinitis caused by Ancylostoma.
Emerging Infectious Diseases. 23;343-344.
Abstract
Albiński M, Hufnagel M, Schelling J, Fleck T, Siepe M, Zieger B, Stiller B (2016)
Cardiac thrombus with risk of fulminant pulmonary embolism in pediatric antiphospholipid syndrome.
Klinische Pädiatrie. 228:219-222.
Abstract
Klotsche J, Raab A, Niewerth M, Sengler C, Ganser G, Kallinich T, Niehues T, Hufnagel M, Thon A, Hospach T, Horneff G, Minden K (2016)
Outcome and trends in treatment of newly diagnosed patients with systemic juvenile idiopathic Arthritis in the National Pediatric Rheumatological Database from 2000 to 2013.
Arthritis & Rheumatology. 2016;68:3023-3034.
Abstract
Bielicki JA, Sharland M, Johnson AP, Henderson KL, Cromwell DA; Antibiotic Resistance and Prescribing in European Children project (2016)
(* Dr. Markus Hufnagel is a contributing member of the ARPEC (Antibiotic Prescribing and Resistance in European Children) Project.)
Selecting appropriate empirical antibiotic regimens for paediatric bloodstream infections: application of a Bayesian decision model to local and pooled antimicrobial resistance surveillance data.
Journal of Antimicrobial Chemotherapy. 71:794-802.
Abstract
Hufnagel M, König S, Theilacker C (2016)
Importance of local epidemiology in prevalence and resistance of cystic fibrosis-related pathogens.
Pediatric Infectious Diseases Journal. 35:229.
Abstract
Jakob A, Whelan J, Kordecki M, Berner R, Stiller B, Arnold R, von Kries R, Roubinis N, Robert M, Grohman J, Höhn R, Hufnagel M (2016)
Kawasaki disease in Germany: A prospective, population-based study adjusted for underreporting.
Pediatric Infectious Diseases Journal. 35:129-134.
Abstract
Grom AA, Ilowite NT, Pascual V, Brunner HI, Martini A, Lovell D, Ruperto N; Paediatric Rheumatology International Trials Organisation and the Pediatric Rheumatology Collaborative Study Group*, Leon K, Lheritier K, Abrams K (2016)
(* Dr. Markus Hufnagel is a contributing member of the Paediatric Rheumatology International Trials Organisation.)
Rate and Clinical Presentation of Macrophage Activation Syndrome in Patients With Systemic Juvenile Idiopathic Arthritis Treated With Canakinumab.
Arthritis and Rheumatology. 68:218-28.
Abstract
Spyridis N, Syridou G, Goossens H, Versporten A, Kopsidas J, Kourlaba G, Bielicki J, Drapier N, Zaoutis T, Tsolia M, Sharland M, ARPEC Project Group* (2016)
(* Dr. Markus Hufnagel is a contributing member of the ARPEC (Antibiotic Prescribing and Resistance in European Children) Project.)
Variation in paediatric hospital antibiotic guidelines in Europe.
Archives of Disease in Childhood. 101:72-6.
Abstract
Rosini R, Campisi E, De Chiara M, Tettelin H, Rinaudo D, Toniolo C, Metruccio M, Guidotti S, Skov Sørensen UB, Kilian M, Ramirez M, DEVANI Consortium*, Janulczyk R, Donati C, Grandi G, Margarit I (2015)
(* Dr. Markus Hufnagel is a contributing member of the DEVANI (Design of a Vaccine Against Neonatal Infections) Study Group.)
Genomic analysis reveals the molecular basis for capsule loss in the group B Streptococcus population.
PLoS ONE. 10:e0125985.
Abstract
Bielicki JA, Lundin R, Sharland M, for the ARPEC Project* (2015)
(* Dr. Markus Hufnagel is a contributing member of the ARPEC (Antibiotic Prescribing and Resistance in European Children) Project.)
Antibiotic resistance prevalence in routine bloodstream isolates from children’s hospitals varies substantially from adult surveillance data in Europe.
Pediatric Infectious Diseases Journal. 34:734-41.
Abstract
Lestner JM, Versporten A, Doerholt K, Warris A, Roilides E, Sharland M, Bielicki J, Goossens H, ARPEC Project Group* (2015)
(* Dr. Markus Hufnagel is a contributing member of the ARPEC (Antibiotic Prescribing and Resistance in European Children) Project.)
Systematic antifungal prescribing in neonates and children: Outcomes from the Antibiotic Resistance and Prescribing in European Children (ARPEC) study.
Antimicrobial Agents and Chemotherapy. 59:782-789.
Abstract
Kunze M, Zumstein K, Markfeld-Erol F, Elling R, Lander F, Prömpeler H, Berner R, Hufnagel M (2015)
Comparison of pre- and intrapartum screening of group B streptococci and adherence to screening guidelines: A cohort study.
European Journal of Pediatrics. 174:827–835.
Abstract
Lenz D, Held J, Goerke S, Wagner D, Tintelnot K, Henneke P, Hufnagel M (2015)
Primary cutaneous cryptococcosis in an eight-year-old immunocompetent child: how to treat?
Klinische Pädiatrie. 227:41-44. German.
Abstract
de Jong MD, Reusken C, Horby P, Koopmans M, Bonten M, Chiche JD, Giaquinto C, Welte T, Leus F, Schotsman J, Goossens H, on behalf of the PREPARE consortium and affiliated clinical networks* (2014)
(* Dr. Markus Hufnagel is a contributing member of the PREPARE Consortium.)
Preparedness for admission of patients with suspected Ebola virus disease in European hospitals: a survey, August-September 2014.
EuroSurveillance 19(48):pii=20980.
Abstract
Da Cunha V, Davies MR, Douarre PE, Rosinski-Chupin I, Margarit I, Spinali S, Perkins T, Lechat P, Dmytruk N, Sauvage E, Ma L, Romi B, Tichit M, Lopez-Sanchez MJ, Descorps-Declere S, Souche E, Buchrieser C, Trieu-Cuot P, Moszer I, Clermont D, Maione D, Bouchier C, McMillan DJ, Parkhill J, Telford JL, Dougan G, Walker MJ; DEVANI Consortium*, Holden MT, Poyart C, Glaser P (2014)
(* Dr. Markus Hufnagel is a contributing member of the DEVANI (Design of a Vaccine Against Neonatal Infections) Study Group.)
Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline.
Nature Communications. 5:4544.
Abstract
D’Urzo N, Martinelli M, Pezzicoli A, De Cesare V, Pinto V, Margarit I, Telford JL, Maione D; Members of the DEVANI Study Group* (2014)
(* Dr. Markus Hufnagel is a contributing member of the DEVANI (Design of a Vaccine Against Neonatal Infections) Study Group.)
Acidic pH strongly enhances in vitro biofilm formation by a subset of hypervirulent ST-17 Streptococcus agalactiae strains.
Applied and Environmental Microbiology. 80:2176-2185.
Abstract
Hufnagel M, Sixel K, Hammer F, Kropec A, Sava IG, Theilacker C, Berner R, Huebner J (2014)
Detection of opsonic antibodies against Enterococcus faecalis cell wall carbohydrates in immune globulin preparations.
Infection. 42:749-755.
Abstract
Puzik A, Geiger J, Hufnagel M (2014)
A young girl with familial Mediterranean fever and abdominal pain.
Clinical Pediatrics. 53:1106-1108.
Abstract
Elling R, Hufnagel M, Imm A, de Zoysa A, Lander F, Zumstein K, Kunze M, Lausch E, Krueger M, Henneke P (2014)
Synchronous recurrence of group B streptococcal late-onset sepsis in twins.
Pediatrics. 133:e1388-e1391.
Abstract
Blessing K, Toepfner N, Kinzer S, Möllmann C, Geiger J, Serr A, Hufnagel M, Müller C, Krüger M, Ridder GJ, Berner R. (2013)
Lemierre syndrome associated with 12th cranial nerve palsy: A case report and review.
International Journal of Pediatric Otorhinolaryngology. 77:1585-1588.
Abstract
Heideking M, Lander F, Hufnagel M, Pfeifer Y, Wicker E, Krause G, Berner R (2013)
Antibiotic susceptibility profiles of neonatal invasive isolates of Escherichia coli from a 2-year nationwide surveillance study in Germany, 2009–2010
European Journal of Clinical Microbiology and Infectious Diseases. 32:1221–1223.
Abstract
Simon A, Müller A, Kaiser P, Töpfner N, Berner R, Laws H-J, Knorr M, Hufnagel M, Beyersdorff A, Heister P, Becker C, Liese JG, Tenenbaum T (2013)
The Paed IC project: Antibiotic stewardship and hospital hygiene to prevent infection with resistant pathogens. [Das Paed IC Projekt: Antibiotic Stewardship und Infektionsprävention zur Vermeidung von nosokomialen Infektionen durch resistente Infektionserreger.]
Klinische Pädiatrie 225; 93-95. German.
Citation
Yao K, Poulsen K, Maione D, Rinaudo CD, Baldassarri L, Telford JL, Sørensen UBS, members of the DEVANI Study Group*, Kilian M (2013)
(* Dr. Markus Hufnagel is a contributing member of the DEVANI (Design of a Vaccine Against Neonatal Infections) Study Group.)
Capsular Gene Typing of Streptococcus agalactiae Compared to Serotyping by Latex Agglutination
Journal of Clinical Microbiology. 51(2):503-7.
Abstract
Toepfner N, Henneke P, Berner R, Hufnagel M (2012)
Impact of technical training on rapid antigen detection tests
(RADT) in group A streptococcal tonsillopharyngitis
European Journal of Clinical Microbiology and Infectious Diseases, 32:609-611.
Abstract
Meinicke H, Heinzmann A, Geiger J, Berner R, Hufnagel M (2012)
Symptoms of Shrinking Lung Syndrome Reveal Systemic Lupus Erythematosus in a 12-Year-Old Girl
Pediatric Pulmonology, 48:1246–1249.
Abstract
Hufnagel M, Henneke P, Schmitt-Graeff A (2012)
IgG4-Related Disease
New England Journal of Medicine. 366:1643-44, Author reply 1646-7.
Abstract
Jakob A, Creutzfeldt R, Staszewski O, Winterpacht A, Berner R, Hufnagel M (2012)
Primary erythromalalgia in a 12-year-old boy: Positive response to sodium channel blockers despite negative SCN9A mutations.
Klinische Pädiatrie. 224:309–312.
Abstract
Farmand S, Henneke P, Hufnagel M, Berner R (2012)
Significant decline in the erythromycin resistance of group A streptococcus isolates at a German paediatric tertiary care centre.
European Journal of Clinical Microbiology and Infectious Diseases. 31:707-710.
Abstract
Jessen B, Maul-Pavicic A, Ufheil H, Vraetz T, Enders A, Lehmberg K, Längler A, Gross-Wieltsch U, Bay A, Kaya Z, Bryceson YT, Koscielniak E, Badawy S, Davies G, Hufnagel M, Schmitt-Gräff A, Aichele P, zur Stadt U, Schwarz K, Ehl S (2011)
Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome.
Blood, 118:4620-4629.
Abstract
Fluegge K, Wons J, Spellerberg B, Swoboda S, Siedler A, Hufnagel M, Berner R (2011)
Genetic Differences Between Invasive and Noninvasive Neonatal Group B Streptococcal Isolate.
Pediatric Infectious Disease Journal. 30:1027-1031
Abstract
Afshar B, Broughton K, Creti R, Detcheva A, Hufnagel M, Kriz P, Lambertsen L, Lovgren M, Melin P, Orefici G, Poyart C, Radtke A, Rodriguez-Granger J, Skov Sørensen UB, Telford J, Valinsky L, Zachariadou L, Members of the DEVANI study group*, Efstratiou A. (2011)
(* Dr. Markus Hufnagel is a contributing member of the DEVANI (Design of a Vaccine Against Neonatal Infections) Study Group.)
International External Quality Assurance for Laboratory Diagnosis and Typing of Streptococcus agalactiae (group B streptococci).
Journal of Clinical Microbiology. 49:1475-1482
Abstract
Maul-Pavicic A, Chiang S, Rensing-Ehl A, Fauriat C, Hufnagel M, Schulze I, Bass T, Schamel W, Schwarz K, Bryceson Y, Ehl S (2011)
Orai1 is required for target cell-induced NK cell degranulation and cytokine production.
Proceedings of the National Academy of Science. 108:3324-3329
Abstract
Schenk T, Maier B, Hufnagel M, Strahm B, Kontny U, Neumann-Haefelin D, Falcone V (2011)
Persistence of human bocavirus DNA in immunocompromised children.
Pediatric Infectious Diseases Journal, 30:82-84
Abstract
Hatz C, Inoubli S, Loutan L, Genton B, Behrens R, Hufnagel M (2010)
Japanese encephalitis: Risk for endemic populations and for travellers. [Encéphalite japonaise: risque pour les populations vivant en zones d'endémie et pour les voyageurs.]
Revue Médicale Suisse, 6(248):956-9. French.
Abstract
Carlsson G, Hufnagel M, Jansen O, Claviez A, Nabavi A (2010)
Rapid recovery of motor and cognitive functions after resection
of a right frontal lobe meningioma in a child.
Child's Nervous System, 26:105-111
Abstract
Hatz C, Werlein J, Mutsch M, Hufnagel M, Behrens RH (2009)
Japanese Encephalitis: Defining Risk Incidence for Travelers to Endemic Countries and Vaccine Prescribing From the UK and Switzerland.
Journal of Travel Medicine, 16:200-203
Abstract
von Schnakenburg C, Hufnagel M, Superti-Furga A, Rieger-Fackeldey E, Berner R (2009)
Successful Continuous Renal Replacement Therapy in a Neonate with Early-onset Group B Streptococcal Sepsis and Multi-organ Dysfunction Syndrome. [Multiorganversagen bei Early-onset-B-Streptokokkensepsis: Erfolgreicher Einsatz einer kontinuierlichen venovenösen Hämofiltration (CVVH) beim Neugeborenen.]
Klinische Pädiatrie, 221:251-3. German.
Abstract
Hufnagel M, Burger A, Bartelt S, Henneke P, Berner R (2008)
Secular trends in pediatric bloodstream infections over a 20-year period at a tertiary care hospital in Germany.
European Journal of Pediatrics, 167:1149-59
Abstract
Hufnagel M, Liese C, Löscher C, Kunze K, Prömpeler H, Berner R, Krüger M (2007)
Enterococcal colonization of infants in a neonatal intensive care unit: Seasonal patterns and associated risk factors.
BMC Infectious Diseases, 7:107
Abstract
Schenk T, Strahm B, Kontny U, Hufnagel M, Neumann-Haefelin D, Falcone V (2007)
Disseminated human bocavirus infection in a child following hematopoietic stem cell transplantation.
Emerging Infectious Diseases, 13:1425-1427
Abstract
Hufnagel M, Carey VJ, Baldassarri L, Reinert RR, Huebner J (2006)
Distribution of four capsular serotypes of Enterococcus faecalis among clinical isolates from different geographical origins and infection sites.
Infection, 34:22-25
Abstract
Buck D, Malivert L, de Chasseval R, Barraud A, Fondanèche M-C, Sanal O, Plebani A, Stèphan J-L, Hufnagel M, le Deist F, Fischer A, Durandy A, de Villartay JP, Revy P (2006)
Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly.
Cell, 124:287-299
Abstract
Hufnagel M, Czech N, Schmidt M, Hero B, Claviez A (2006)
Neuroblastoma Stage 4S with 123I-MIBG-positive bone marrow involvement.
Pediatric Blood & Cancer, 46:264-265
Citation
Hufnagel M, Huebner J (2005)
Analysis of the specific immune response against capsular polysaccharides of two patients with systemic enterococcal infections.
Infection, 33:373-376
Abstract
Kropec A, Hufnagel M, Zimmermann K, Huebner J (2005)
In vitro assessment of the host response against Enterococcus faecalis in probiotic preparations.
Infection, 33:377-379
Abstract
Hufnagel M, Kropec A, Theilacker C, Huebner J (2005)
Naturally acquired antibodies against four Enterococcus faecalis capsular polysaccharides in normal human sera.
Clinical and Vaccine Immunology (formerly Clinical and Diagnostic Laboratory Immunology), 12:930-934
Abstract
Hufnagel M, Hancock LE, Koch S, Theilacker C, Gilmore MS, Huebner J (2004)
Serological and genetic diversity of capsular polysaccharides in Enterococcus faecalis.
Journal of Clinical Microbiology, 42:2548-2557
Abstract
Hufnagel M, Koch S, Creti R, Baldassarri L, Huebner J (2004)
A putative sugar-binding transcriptional regulator in a novel gene locus in Enterococcus faecalis contributes to biofilm formation and prolonged bacteremia in mice.
Journal of Infectious Diseases, 189:420-430
Abstract
Hufnagel M, Koch S, Kropec A, Huebner J (2003)
Opsonophagocytic assay as a potentially useful tool for assessing safety of Enterococcal preparation.
International Journal of Food Microbiology, 88:263-267
Abstract
Lässker U, Harder TC, Hufnagel M, Suttorp M (2002)
Rapid molecular discrimination of infection with wild-type varicella zoster virus or varicella vaccine virus.
Infection, 30:320-322
Abstract
Harder TC, Hufnagel M, Zahn K, Beutel K, Schmitt HJ, Ullmann U, Rautenberg P (2001)
A new LightCycler™ polymerase chain reaction for rapid and sensitive quantification of parvovirus B19 DNA guides therapeutic decision-making in chronic infections.
Journal of Clinical Microbiology, 39:4413-4419
Abstract
Eichmann D, Hufnagel M, Quick P, Santer R (1999)
Treatment of hyperinsulinemic hypoglycemia with nifedipine.
European Journal of Pediatrics, 158:204-206
Abstract
Muller D, Hufnagel M, Suttorp (1999)
Accidental overdose of vancomycin in preterm twins.
Pediatric Infectious Diseases Journal, 18:744-745
Citation
Hufnagel M, Eichmann D, Stieh J, Santer R (1998)
Further evidence for a dominant form of familial persistent hyperinsulinemic hypoglycemia of infancy: a family with documented hyperinsulinemia in two generations.
Journal of Clinical Endocrinology and Metabolism, 83:2215-2216
Citation
Dai WJ, Bartens W, Kohler G, Hufnagel M, Kopf M, Brombacher F (1997)
Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes-infected IFN-gamma receptor-deficient mice.
Journal of Immunology, 158:5297-5304.
Abstract
Hufnagel M, Niemeyer C, Zimmerhackl LB, Tuchelmann T, Sauter S, Brandis M (1995)
Hemophagocytosis: a complication of acute Q fever in a child.
Clinical Infectious Diseases, 21:1029-1031.
Abstract
Hufnagel M, Tuchelmann, Zimmerhackl LB, Leititis JU, Tüchelmann T, Brandis M, Brem S, Schindera F (1994)
Acute renal failure without liver involvement in Leptospirosis icterohaemorrhagiae infection. [Akutes Nierenversagen ohne Leberbeteiligung bei Leptospira icterohaemorrhagiae-Infektion.]
Monatsschrift Kinderheilkunde 142:957-960. German.
Citation
Dr. Markus Hufnagel is a specialist in pediatric and adolescent medicine, infectious diseases, pediatric rheumatology, immunology, tropical medicine, travel medicine and vaccinology. As Director of Pediatric Rheumatology and Deputy Director of Pediatric Infectious Diseases at the University Children's Hospital in Freiburg, Germany, Dr. Hufnagel is responsible for patient care and care management, medical teaching and medical research. His current research focuses on antibiotic usage and resistance, epidemiology of COVID-19, infections with gram-positive pathogens, medical care of refugees and quality of care of pediatric rheumatology patients. Active in numerous international projects, Dr. Hufnagel regularly collaborates with European and North American partners, as well as with several NGOs working in resource-poor countries.
